Publications

2024

Lengyel, Kamila; Rudra, Mekhla; Berghof, Tom V. L.; Leitão, Albertine; Frankl-Vilches, Carolina; Dittrich, Falk; Duda, Denise; Klinger, Romina; Schleibinger, Sabrina; Sid, Hicham; Trost, Lisa; Vikkula, Hanna; Schusser, Benjamin; Gahr, Manfred: Unveiling the critical role of androgen receptor signaling in avian sexual development. Nature Communications 15 (1), 2024 mehr…
Sabsabi, Mohammad A.; Kheimar, Ahmed; You, Yu; von La Roche, Dominik; Härtle, Sonja; Göbel, Thomas W.; von Heyl, Theresa; Schusser, Benjamin; Kaufer, Benedikt B.: Unraveling the role of γδ T cells in the pathogenesis of an oncogenic avian herpesvirus. mBio, 2024 mehr…
Volf, Jiri; Kaspers, Bernd; Schusser, Benjamin; Crhanova, Magdalena; Karasova, Daniela; Stepanova, Hana; Babak, Vladimir; Rychlik, Ivan: Immunoglobulin secretion influences the composition of chicken caecal microbiota. Scientific Reports 14 (1), 2024 mehr…

2023

Flisikowska, Tatiana: Humanized minipigs to assess drug safety. Nature Reviews Cancer 23 (7), 2023, 427-427 mehr…
Hansen, Sabrina; Fischer, Konrad; Krabben, Ludwig; Rinke Carrapeiro, Alexander; Klinger, Bernhard; Schnieke, Angelika; Kaufer, Benedikt; Denner, Joachim: Detection of porcine cytomegalovirus, a roseolovirus, in pig ovaries and follicular fluid: implications for somatic cells nuclear transfer, cloning and xenotransplantation. Virology Journal 20 (1), 2023 mehr…
Kollmansperger, Sandra; Anders, Malte; Werner, Julia; Saller, Anna M.; Weiss, Larissa; Süß, Stephanie C.; Reiser, Judith; Schneider, Gerhard; Schusser, Benjamin; Baumgartner, Christine; Fenzl, Thomas: Nociception in chicken embryos, Part II: Embryonal development of electroencephalic neuronal activity in ovo as a prerequisite for nociception. bioRxiv, 2023 mehr…
Lo, Wan-Lin; Kuhlmann, Miriam; Rizzuto, Gabrielle; Ekiz, H. Atakan; Kolawole, Elizabeth M.; Revelo, Monica P.; Andargachew, Rakieb; Li, Zhongmei; Tsai, Yuan-Li; Marson, Alexander; Evavold, Brian D.; Zehn, Dietmar; Weiss, Arthur: A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function. Nature Immunology 24 (4), 2023, 676-689 mehr…
Malhotra, Deepika; Fattahi, Ehsan; Germann, Natalie; Flisikowska, Tatiana; Schnieke, Angelika; Becker, Thomas: Skin substitutes based on gellan gum with mechanical and penetration compatibility to native human skin. Journal of Biomedical Materials Research Part A 111 (10), 2023, 1588-1599 mehr…
Malhotra, Deepika; Fattahi, Ehsan; Germann, Natalie; Flisikowska, Tatiana; Schnieke, Angelika; Becker, Thomas: Skin substitutes based on gellan gum with mechanical and penetration compatibility to native human skin. Journal of Biomedical Materials Research Part A 111 (10), 2023, 1588-1599 mehr…
Marx, Anna-Friederike; Kallert, Sandra M.; Brunner, Tobias M.; Villegas, José A.; Geier, Florian; Fixemer, Jonas; Abreu-Mota, Tiago; Reuther, Peter; Bonilla, Weldy V.; Fadejeva, Jelizaveta; Kreutzfeldt, Mario; Wagner, Ingrid; Aparicio-Domingo, Patricia; Scarpellino, Leo; Charmoy, Mélanie; Utzschneider, Daniel T.; Hagedorn, Claudia; Lu, Min; Cornille, Karen; Stauffer, Karsten; Kreppel, Florian; Merkler, Doron; Zehn, Dietmar; Held, Werner; Luther, Sanjiv A.; Löhning, Max; Pinschewer, Daniel D.: The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1+ CD8+ T cells in chronic viral infection. Immunity 56 (4), 2023, 813-828.e10 mehr…
Morticelli, Lucrezia; Rossdam, Charlotte; Cajic, Samanta; Böthig, Dietmar; Magdei, Mikhail; Tuladhar, Sugat Ratna; Petersen, Björn; Fischer, Konrad; Rapp, Erdmann; Korossis, Sotirios; Haverich, Axel; Schnieke, Angelika; Niemann, Heiner; Buettner, Falk F. R.; Hilfiker, Andres: Genetic knockout of porcine GGTA1 or CMAH/GGTA1 is associated with the emergence of neo‐glycans. Xenotransplantation 30 (4), 2023 mehr…
Paul, Mariel C.; Schneeweis, Christian; Falcomatà, Chiara; Shan, Chuan; Rossmeisl, Daniel; Koutsouli, Stella; Klement, Christine; Zukowska, Magdalena; Widholz, Sebastian A.; Jesinghaus, Moritz; Heuermann, Konstanze K.; Engleitner, Thomas; Seidler, Barbara; Sleiman, Katia; Steiger, Katja; Tschurtschenthaler, Markus; Walter, Benjamin; Weidemann, Sören A.; Pietsch, Regina; Schnieke, Angelika; Schmid, Roland M.; Robles, Maria S.; Andrieux, Geoffroy; Boerries, Melanie; Rad, Roland; Schneider, Günter; Saur, Dieter: Non-canonical functions of SNAIL drive context-specific cancer progression. Nature Communications 14 (1), 2023 mehr…
Preisinger, David; Winogrodzki, Thomas; Klinger, Bernhard; Schnieke, Angelika; Rieblinger, Beate: Genome Editing in Pigs. In: Methods in Molecular Biology. Springer US, 2023 mehr…
Scherer, Stefanie; Oberle, Susanne G.; Kanev, Kristiyan; Gerullis, Ann-Katrin; Wu, Ming; de Almeida, Gustavo P.; Puleston, Daniel J.; Baixauli, Francesc; Aly, Lilian; Greco, Alessandro; Nizharadze, Tamar; Becker, Nils B.; Hoesslin, Madlaina v.; Donhauser, Lara V.; Berner, Jacqueline; Chu, Talyn; McNamara, Hayley A.; Esencan, Zeynep; Roelli, Patrick; Wurmser, Christine; Kleiter, Ingo; Vehreschild, Maria J. G. T.; Mayer, Christoph A.; Knolle, Percy; Klingenspor, Martin; Fumagalli, Valeria; Iannacone, Matteo; Prlic, Martin; Korn, Thomas; Pearce, Erika L.; Höfer, Thomas; Schulz, Anna M.; Zehn, Dietmar: Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T cell development. Nature Immunology 24 (3), 2023, 501-515 mehr…
Schulz, Anna M.; Zebley, Caitlin C.; Youngblood, Ben; Zehn, Dietmar: Tapping the keg of discovery to advance T cell therapy. Nature Immunology 24 (2), 2023, 213-215 mehr…
Soerens, Andrew G.; Künzli, Marco; Quarnstrom, Clare F.; Scott, Milcah C.; Swanson, Lee; Locquiao, JJ.; Ghoneim, Hazem E.; Zehn, Dietmar; Youngblood, Benjamin; Vezys, Vaiva; Masopust, David: Functional T cells are capable of supernumerary cell division and longevity. Nature 614 (7949), 2023, 762-766 mehr…
Suess, Stephanie Christina; Werner, Julia; Saller, Anna Maria; Weiss, Larissa; Reiser, Judith; Ondracek, Janie Michelle; Zablotski, Yury; Kollmansperger, Sandra; Anders, Malte; Schusser, Benjamin; Fenzl, Thomas; Baumgartner, Christine: Nociception in chicken embryos, Part III: Analysis of movements before and after application of a noxious stimulus. bioRxiv, 2023 mehr…
Theresa von Heyl Romina Klinger Dorothea Aumann Christian Zenner Mohanned Alhussien Antonina Schlickenrieder Kamila Lengyel Hanna-Kaisa Vikkula Teresa Mittermair Hicham Sid Benjamin Schusser: Knockout of αβ but not γδ T cells in chickens is associated with high cytotoxicity and deficiency of regulatory and helper T cells. biorxiv, 2023 mehr…
Weiss, Larissa; Saller, Anna M.; Werner, Julia; Süß, Stephanie C.; Reiser, Judith; Kollmansperger, Sandra; Anders, Malte; Fenzl, Thomas; Schusser, Benjamin; Baumgartner, Christine: Nociception in chicken embryos, Part I: Analysis of cardiovascular responses to a mechanical noxious stimulus. bioRxiv, 2023 mehr…
Weiss, Larissa; Saller, Anna M.; Werner, Julia; Süß, Stephanie C.; Reiser, Judith; Kollmansperger, Sandra; Anders, Malte; Potschka, Heidrun; Fenzl, Thomas; Schusser, Benjamin; Baumgartner, Christine: Nociception in Chicken Embryos, Part I: Analysis of Cardiovascular Responses to a Mechanical Noxious Stimulus. Animals 13 (17), 2023, 2710 mehr…
Winogrodzki, Thomas; Metwaly, Amira; Grodziecki, Alessandro; Liang, Wei; Klinger, Bernhard; Flisikowska, Tatiana; Fischer, Konrad; Flisikowski, Krzysztof; Steiger, Katja; Haller, Dirk; Schnieke, Angelika: TNF ΔARE Pigs: A Translational Crohn’s Disease Model. Journal of Crohn's and Colitis 17 (7), 2023, 1128-1138 mehr…

2022

Chin, Shu Shien; Guillen, Erik; Chorro, Laurent; Achar, Sooraj; Ng, Karina; Oberle, Susanne; Alfei, Francesca; Zehn, Dietmar; Altan-Bonnet, Grégoire; Delahaye, Fabien; Lauvau, Grégoire: T cell receptor and IL-2 signaling strength control memory CD8+ T cell functional fitness via chromatin remodeling. Nature Communications 13 (1), 2022 mehr…
Dähling, Sabrina; Mansilla, Ana Maria; Knöpper, Konrad; Grafen, Anika; Utzschneider, Daniel T.; Ugur, Milas; Whitney, Paul G.; Bachem, Annabell; Arampatzi, Panagiota; Imdahl, Fabian; Kaisho, Tsuneyasu; Zehn, Dietmar; Klauschen, Frederick; Garbi, Natalio; Kallies, Axel; Saliba, Antoine-Emmanuel; Gasteiger, Georg; Bedoui, Sammy; Kastenmüller, Wolfgang: Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches. Immunity 55 (4), 2022, 656-670.e8 mehr…
Flisikowska, Tatiana; Egli, Jerome; Flisikowski, Krzysztof; Stumbaum, Marlene; Küng, Erich; Ebeling, Martin; Schmucki, Roland; Georges, Guy; Singer, Thomas; Kurome, Mayuko; Kessler, Barbara; Zakhartchenko, Valeri; Wolf, Eckhard; Weber, Felix; Schnieke, Angelika; Iglesias, Antonio: A humanized minipig model for the toxicological testing of therapeutic recombinant antibodies. Nature Biomedical Engineering 6 (11), 2022, 1248-1256 mehr…
Koerber, Nina; Priller, Alina; Yazici, Sarah; Bauer, Tanja; Cheng, Cho-Chin; Mijočević, Hrvoje; Wintersteller, Hannah; Jeske, Samuel; Vogel, Emanuel; Feuerherd, Martin; Tinnefeld, Kathrin; Winter, Christof; Ruland, Jürgen; Gerhard, Markus; Haller, Bernhard; Christa, Catharina; Zelger, Otto; Roggendorf, Hedwig; Halle, Martin; Erber, Johanna; Lingor, Paul; Keppler, Oliver; Zehn, Dietmar; Protzer, Ulrike; Knolle, Percy A.: Dynamics of spike-and nucleocapsid specific immunity during long-term follow-up and vaccination of SARS-CoV-2 convalescents. Nature Communications 13 (1), 2022 mehr…
Richter, Phil; Sebald, Karin; Fischer, Konrad; Behrens, Maik; Schnieke, Angelika; Somoza, Veronika: Bitter Peptides YFYPEL, VAPFPEVF, and YQEPVLGPVRGPFPIIV, Released during Gastric Digestion of Casein, Stimulate Mechanisms of Gastric Acid Secretion via Bitter Taste Receptors TAS2R16 and TAS2R38. Journal of Agricultural and Food Chemistry 70 (37), 2022, 11591-11602 mehr…
Salvermoser, Lukas; Flisikowski, Krzysztof; Dressel-Böhm, Susann; Nytko, Katarzyna J.; Rohrer Bley, Carla; Schnieke, Angelika; Samt, Ann-Kathrin; Thölke, Dennis; Lennartz, Philipp; Schwab, Melissa; Wang, Fei; Bashiri Dezfouli, Ali; Multhoff, Gabriele: Elevated circulating Hsp70 levels are correlative for malignancies in different mammalian species. Cell Stress and Chaperones 28 (1), 2022, 105-118 mehr…
Schulz, Anna M; Zehn, Dietmar: Mastering an exhausting marathon: how CD8 + T cells fine‐tune metabolic fitness. Immunology & Cell Biology 100 (2), 2022, 83-86 mehr…
Schusser, Benjamin; Doran, Timothy: Advances in genetic engineering of the avian genome. In: Avian Immunology. Elsevier, 2022 mehr…
Tsui, Carlson; Kretschmer, Lorenz; Rapelius, Svenja; Gabriel, Sarah S.; Chisanga, David; Knöpper, Konrad; Utzschneider, Daniel T.; Nüssing, Simone; Liao, Yang; Mason, Teisha; Torres, Santiago Valle; Wilcox, Stephen A.; Kanev, Krystian; Jarosch, Sebastian; Leube, Justin; Nutt, Stephen L.; Zehn, Dietmar; Parish, Ian A.; Kastenmüller, Wolfgang; Shi, Wei; Buchholz, Veit R.; Kallies, Axel: MYB orchestrates T cell exhaustion and response to checkpoint inhibition. Nature 609 (7926), 2022, 354-360 mehr…
Zehn, Dietmar; Thimme, Robert; Lugli, Enrico; de Almeida, Gustavo Pereira; Oxenius, Annette: ‘Stem-like’ precursors are the fount to sustain persistent CD8+ T cell responses. Nature Immunology 23 (6), 2022, 836-847 mehr…
von Hoesslin, Madlaina; Kuhlmann, Miriam; de Almeida, Gustavo Pereira; Kanev, Kristiyan; Wurmser, Christine; Gerullis, Ann-Katrin; Roelli, Patrick; Berner, Jacqueline; Zehn, Dietmar: Secondary infections rejuvenate the intestinal CD103 + tissue-resident memory T cell pool. Science Immunology 7 (77), 2022 mehr…